From Channing Tatum and Winona Ryder, to Bill Murray and Matthew McConaughey, Da Bomb Beyond Insanity had its way with Hot Ones guests all year long—not to mention Sean Evans, from time to time. Take a look back at some of 2025’s best reactions to the infamous #8 sauce in the Hot Ones lineup—including Kai Cenat’s scream heard round the world!
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